Perusing the space for ideas, I found this link somewheres - I think I followed the Moleskinerie link here and eventually ended up on YouTube. I admire this work by Takayashi Yoshinari. He, or maybe she, has created a single piece, 'Flow', which runs throughout the book, leading on from the previous page. It's such a simple idea, but beautifully executed. I especially like the way they've imagined a virtual extension to some of the pages and left the real page only to join it again at a different point, often a different page. Why don't I think of these things?!
There are several in this collection from 2006 on YouTube. At least a couple of contributors, Valeria Petrone, and Ted Goff, started by drawing two similar sized cells on each side of every page and used these as frames. I like that idea too.
PS. numpty that I am, it's only just occurred to me that these two approaches are polar opposites!